Chronic inflammation and abdominal obesity can together cause and worsen several diseases. Metabolically active abdominal fat, especially visceral fat, can create inflammatory chemicals, causing chronic low-grade inflammation.
Cytokines, Adipokines: Cytokines and adipokines like interleukin-6 and leptin are released by visceral fat. These chemicals can cause and maintain systemic inflammation.
Insulin Resistance: Excessive abdominal fat is linked to insulin resistance, that reduces cell responsiveness to insulin. Insulin resistance causes metabolic dysfunction and inflammation.
Metabolic Syndrome Parts: Chronic inflammation is central to metabolic syndrome, which includes abdominal obesity, insulin resistance, elevated blood pressure, and abnormal cholesterol levels. These factors raise cardiovascular disease, type 2 diabetes, and other health risks.
Cardiovascular Diseases: Atherosclerosis: Chronic inflammation contributes to plaque formation in artery walls. Hypertension and dyslipidemia are linked to abdominal fat.
Cancer: Inflammatory Microenvironment: Chronic inflammation can increase cancer start and progression. Obesity and inflammation raise the risk of colorectal, breast, and pancreatic cancers.
Respiratory Disorders: - Inflammatory Lung Conditions: - Abdominal obesity is linked to asthma and obstructive sleep apnea. Chronic inflammation may worsen these illnesses.
To control and prevent the effects of chronic inflammation and belly obesity on health, people should take a comprehensive approach to health, including frequent medical checkups.
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